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Cytochromes P450 in gibberellin biosynthesis


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Davidson, SE and Reid, JB and Helliwell, CA (2006) Cytochromes P450 in gibberellin biosynthesis. Phytochemistry Reviews, 5. pp. 405-419. ISSN 1568-7767

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The gibberellins (GAs) are an important class of plant growth regulators that are active in many aspects of plant growth and development. GAs are synthesized by a complex pathway involving three enzyme classes spanning different subcellular compartments. One of these enzyme classes is the cytochrome P450s which catalyze a number of oxidation steps in the middle part of the pathway. Mutants in these cytochrome P450-mediated steps in a number of species have been crucial in isolating the genes encoding these enzymes and have also played an important role in understanding GA physiology. GAs are also synthesized by fungi, in a biosynthesis pathway largely catalyzed by cytochrome P450s. The fungal pathway appears to have evolved independently to that of higher plants.

Item Type: Article
Journal or Publication Title: Phytochemistry Reviews
Page Range: pp. 405-419
ISSN: 1568-7767
Identification Number - DOI: 10.1007/s11101-006-9005-5
Additional Information: The final publication is available at
Date Deposited: 19 Aug 2011 02:32
Last Modified: 18 Nov 2014 04:21
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