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The value of clinical trials: A New Zealand case study

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Murphy, LM (2012) The value of clinical trials: A New Zealand case study. PhD thesis, University of Tasmania.

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Abstract

Objective:
The research question addressed in this thesis is - ‘What is the value of conducting sponsored
clinical trials in a publicly funded New Zealand hospital?’
Methods:
The research design is a simultaneous parallel mixed method design that incorporates two
strands (1) A quantitative analysis of economic outcomes and (2) a qualitative analysis of
perceived value. In the first strand, quantitative methods draw on the data relating to two
sponsored clinical trials. The data include Ministry of Health data, The Centre for Clinical
Research and Effective Practice (CCRep) profit and loss statements, Counties Manukau District
Health Board (CMDHB) annual reports and Chronic Care Management (CCM) data and results
from a health outcome co-study. The second strand uses qualitative methods to explore the
benefits and costs of sponsored clinical trials perceived by stakeholders. The study gathers data
using focus groups, interviews and surveys and adopts a qualitative descriptive approach
followed by a phenomenographical analysis.
Results: The economics outcomes strand finds that CCRep, CMDHB and New Zealand society
all derive financial benefits from these trials. The magnitude of the economic benefits differs
depending on the perspective taken. Both CCRep and CMDHB have benefits that are positive
but small. The largest and potentially the most controversial benefit is a benefit to New Zealand
society of over 373,000 dollars. The qualitative results suggest that the benefits of conducting
sponsored clinical trials within a publicly funded New Zealand hospital outweigh the costs in
respect of all stakeholder groups. The results allow classification of the stakeholders into three
layers: societal; where benefits and costs are filtered by political and social opinions;
organisational; where benefits and costs are seen in terms of their influence on organisational
functions and personal; where benefits and costs are seen as contributing to the psycho-social,
cognitive, physical and behavioural needs of individuals.
Conclusion: Public bodies must be mindful of the wider economic, social and cultural
implications of their activities. This study demonstrates the value created from conducting
clinical trials. The adoption of qualitative and quantitative methods to measure this value
produces a more rounded analysis than would be the product of either approach on its own.

Item Type: Thesis (PhD)
Keywords: health value, clinical trials, cost benefit analysis, mixed method, stakeholder, public perception
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Date Deposited: 17 Aug 2012 04:54
Last Modified: 11 Mar 2016 05:53
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