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Adverse effects of lag filters used for detector baseline noise suppression in HPLC.

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Haddad, PR and Keating, RW and Low, GKC (1982) Adverse effects of lag filters used for detector baseline noise suppression in HPLC. Journal of Liquid Chromatography, 5 (5). pp. 853-867. ISSN 1520-572X (electronic) 1082-6076 (paper)

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Abstract

Most detectors used for High Performance Liquid Chromatography employ a lag filter for suppression of baseline noise. This filter is characterised by its time constant, . At high values of (in excess of 0.5 sec), the lag filter seriously distorts the shape of a chromatographic peak, causing reduced peak heights, altered retention times and increased peak width. These changes result in significantly decreased resolution and decreased plate counts. These effects are investigated quantitatively.

Item Type: Article
Journal or Publication Title: Journal of Liquid Chromatography
Page Range: pp. 853-867
ISSN: 1520-572X (electronic) 1082-6076 (paper)
Identification Number - DOI: 10.1080/01483918208060618
Additional Information: copyright Taylor and Francis
Date Deposited: 01 Apr 2008 03:51
Last Modified: 18 Nov 2014 03:31
URI: http://eprints.utas.edu.au/id/eprint/3485
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