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Adverse effects of lag filters used for detector baseline noise suppression in HPLC.
Haddad, PR and Keating, RW and Low, GKC (1982) Adverse effects of lag filters used for detector baseline noise suppression in HPLC. Journal of Liquid Chromatography, 5 (5). pp. 853-867. ISSN 1520-572X (electronic) 1082-6076 (paper)
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Most detectors used for High Performance Liquid Chromatography employ a lag filter for suppression of baseline noise. This filter is characterised by its time constant, . At high values of (in excess of 0.5 sec), the lag filter seriously distorts the shape of a chromatographic peak, causing reduced peak heights, altered retention times and increased peak width. These changes result in significantly decreased resolution and decreased plate counts. These effects are investigated quantitatively.
|Journal or Publication Title:||Journal of Liquid Chromatography|
|Page Range:||pp. 853-867|
|ISSN:||1520-572X (electronic) 1082-6076 (paper)|
|Identification Number - DOI:||10.1080/01483918208060618|
copyright Taylor and Francis
|Date Deposited:||01 Apr 2008 03:51|
|Last Modified:||18 Nov 2014 03:31|
|Item Statistics:||View statistics for this item|
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