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Sam, Sahh and Map gene expression during cell division and paralytic shellfish toxin production of Alexandrium catenella (Dinophyceae)

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Harlow, LD and Negri, AP and Hallegraeff, GM and Koutoulis, A (2007) Sam, Sahh and Map gene expression during cell division and paralytic shellfish toxin production of Alexandrium catenella (Dinophyceae). Phycologia, 46 (6). pp. 666-674. ISSN 0031-8884

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Abstract

The expression of genes potentially involved in paralytic shellfish toxin (PST) biosynthesis was quantified during cell division of the dinoflagellate Alexandrium catenella. Basic precursors of the neurotoxic PST molecule(s), such as S-adenosylmethionine (SAM), have been hypothesised, but no genes coding for PST production have been definitively identified in dinoflagellates. Sam encodes the enzyme SAM synthetase and two other candidate PST genes S-adenosylhomocysteine hydrolase (Sahh) and methionine aminopeptidase (Map) have been previously identified in the closely related PST producing dinoflagellate Alexandrium fundyense. PST production and expression of Sam, Sahh and Map were examined concurrently during cell division in A. catenella.

Item Type: Article
Journal or Publication Title: Phycologia
Publisher: International Phycological Society
Page Range: pp. 666-674
ISSN: 0031-8884
Identification Number - DOI: 10.2216/07-25.1
Date Deposited: 07 Apr 2008 14:30
Last Modified: 18 Nov 2014 03:35
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