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Long-acting beta2-agonists for chronic asthma in adults and children where background therapy contains varied or no inhaled corticosteroid (Review)

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Walters, EH and Gibson, PG and Lasserson, TJ and Walters, JAE (2007) Long-acting beta2-agonists for chronic asthma in adults and children where background therapy contains varied or no inhaled corticosteroid (Review). Cochrane Database of Systematic Reviews (3). pp. 1-285. ISSN 1469-493X

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Abstract

Asthma is a common respiratory disease among both adults and children and short acting inhaled beta-2 agonists are used widely for
’reliever’ bronchodilator therapy. Long acting beta-2 agonists (LABA) were introduced as prospective ’symptom controllers’ in addition
to inhaled corticosteroid ’preventer’ therapy (ICS). In this updated review we have included studies in which patients were either not
on ICS as a group, or in which some patients, but not all, were on ICS to complement previous systematic reviews of studies where
LABA was given in patients uniformly receiving ICS.We have focussed particularly on serious adverse events, given previous concerns
about potential risks, especially of death, from regular beta-2 agonist use.

Item Type: Article
Journal or Publication Title: Cochrane Database of Systematic Reviews
Publisher: John Wiley & Sons Ltd
Page Range: pp. 1-285
ISSN: 1469-493X
Identification Number - DOI: 10.1002/14651858.CD001385.pub2
Date Deposited: 07 Apr 2008 14:37
Last Modified: 18 Nov 2014 03:35
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