Methyl 4-chloro-3,5-di-p-tolyl-1H-pyrrole-2-carboxylate dichloromethane hemisolvate

Abstract

Recently, we have developed a synthetic procedure that allows the controlled formation of mono- and diarylpyrroles by chemoselective Suzuki–Miyaura coupling (Smith et al., 2006). The key to the method was using chloride as a blocking group which is not very reactive for cross-coupling, and then its removal by catalytic hydrogenation.