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In vitro biosynthesis of androgens in the Australian lungfish, Neoceratodus forsteri
Joss, JMP and Edwards, A and Kime, DE (1996) In vitro biosynthesis of androgens in the Australian lungfish, Neoceratodus forsteri. General and Comparative Endocrinology, 101 (3). pp. 235-343. ISSN 0016-6480
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The serum concentration of testosterone was estimated from a population of wild lungfish over 6–7 years of sampling. Male lungfish were found to have high circulating levels of testosterone (50 ng/ml) which varied seasonally and could be correlated with spermatogenesis as judged by testis histology. Incubation of testis tissue slices with [3H]progesterone, [3H]17-hydroxyprogesterone, or [3H]testosterone confirmed that testosterone is the major androgen inNeoceratodus.Not even trace amounts of 11-keto- or 11β-hydroxytestosterone or 5α-dihydrotestosterone could be identified by TLC separations. There was little or no conjugation of steroids by the testes, except during the spawning season, when glucuronides of androstenedione and testosterone were produced.
|Journal or Publication Title:||General and Comparative Endocrinology|
|Page Range:||pp. 235-343|
|Identification Number - DOI:||10.1006/gcen.1996.0028|
|Date Deposited:||18 Jan 2007|
|Last Modified:||18 Nov 2014 03:12|
|Item Statistics:||View statistics for this item|
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