Library Open Repository

Hop mosaic virus: complete nucleotide sequence and relationship to other carlaviruses

Downloads

Downloads per month over past year

Poke, FS (2008) Hop mosaic virus: complete nucleotide sequence and relationship to other carlaviruses. Archives of Virology, 153 (8). pp. 1615-1619. ISSN 0304-8608

[img] PDF
Poke_Arch_Virol.pdf | Request a copy
Full text restricted

Abstract

Hop mosaic virus (HpMV) is an important virus affecting hop (Humulus lupulus L.). It has been detected in all the major hop-growing regions of the world, and its negative impact upon growth, cone yield and levels of brewing acids has been documented [8]. HpMV belongs to the family Flexiviridae and the genus Carlavirus [1]. Typically, carlaviruses are rod-shaped viruses with a positive, singlestrand RNA genome encapsulated by coat protein. The organisation of the genome includes six open reading frames (ORFs), a 50 cap and a 30 poly(A) tail. The structure and organisation of the genome is conserved among the carlaviruses [1]. ORF1 encodes the viral replicase and accounts for more than 70% of the length of the genome sequence. This ORF is composed of several functional domains which contribute to viral replication and which have a conserved amino acid sequence and order [7]. ORFs 2, 3 and 4 make up the triple gene block. These coding regions overlap and encode three proteins (TGBP 1, 2 and 3) that are thought to act in concert to enable virus movement between cells. ORF 5 encodes the coat protein and is overlapped by ORF 6, which encodes a nucleic acidbinding protein that has a putative role as a suppressor of RNA silencing [7]. The complete genome sequence has so far been reported for 19 carlaviruses (plus the complete coding sequence for one other) and varies from 8.2 to 9.1 kilobases (kb), excluding the poly(A) tail.

Item Type: Article
Journal or Publication Title: Archives of Virology
Page Range: pp. 1615-1619
ISSN: 0304-8608
Identification Number - DOI: 10.1007/s00705-008-0157-z
Additional Information: The original publication is available at www.springerlink.com
Date Deposited: 28 Jul 2008 03:59
Last Modified: 18 Nov 2014 03:46
URI: http://eprints.utas.edu.au/id/eprint/7155
Item Statistics: View statistics for this item

Repository Staff Only (login required)

Item Control Page Item Control Page