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Analysis of extended HLA haplotypes in multiple sclerosis and narcolepsy families confirms a predisposing effect for the class I region in Tasmanian MS patients

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Rubio, JP and Bahlo, M and Stankovich, J and Burfoot, RK and Johnson, LJ and Butzkueven, H and Lin, L and Taylor, BV and Speed, TP and Kilpatrick, TJ and Mignot, E and Foote, SJ (2007) Analysis of extended HLA haplotypes in multiple sclerosis and narcolepsy families confirms a predisposing effect for the class I region in Tasmanian MS patients. Immunogenetics, 59 (4). pp. 177-186. ISSN 0093-7711

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Abstract

Human leucocyte antigen (HLA)-DRB1*15 is
associated with predisposition to multiple sclerosis (MS),
although conjecture surrounds the possible involvement of
an alternate risk locus in the class I region of the HLA
complex. We have shown previously that an alternate MS
risk allele(s) may be encompassed by the telomerically
extended DRB1*15 haplotype, and here, we have attempted
to map the putative variant.

Item Type: Article
Journal or Publication Title: Immunogenetics
Page Range: pp. 177-186
ISSN: 0093-7711
Identification Number - DOI: 10.1007/s00251-006-0183-5
Additional Information:

The original publication is available at www.springerlink.com

Date Deposited: 28 Jul 2008 05:31
Last Modified: 18 Nov 2014 03:47
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