Application of high-performance liquid chromatography to the investigation of free radical reactions in biological systems

Glod, BK and Czapski, GA and Haddad, PR (2000) Application of high-performance liquid chromatography to the investigation of free radical reactions in biological systems. TrAC - Trends in Analytical Chemistry, 19 (8). pp. 492-497. ISSN 0167-2940

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Official URL: http://dx.doi.org/10.1016/S0165-9936(00)00018-2

Abstract

The determination of free radicals and their reaction products in biological systems is discussed, with an emphasis on the use of liquid chromatographic methods for the analysis. Free radicals formed from oxygen and its reduction products, nitric oxide, and lipid radicals are considered. Whilst reversed-phase high-performance liquid chromatography has found wide application for these analyses, ion-exclusion chromatography also has significant potential and some developments in this area are described.

Item Type:	Article
Additional Information:	The definitive version is available at http://www.sciencedirect.com
Keywords:	High-performance liquid chromatography; Ion exclusion chromatography; Reactive oxygen species; Free radicals; Nitric oxide; Malonyldialdehyde
ID Code:	7918
Deposited By:	Mr Marcus Guijt
Deposited On:	31 Oct 2008 16:49
Last Modified:	31 Oct 2008 16:49
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