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Application of high-performance liquid chromatography to the investigation of free radical reactions in biological systems

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Glod, BK and Czapski, GA and Haddad, PR (2000) Application of high-performance liquid chromatography to the investigation of free radical reactions in biological systems. TrAC - Trends in Analytical Chemistry, 19 (8). pp. 492-497. ISSN 0167-2940

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Abstract

The determination of free radicals and their reaction products in biological systems is discussed, with an emphasis on the use of liquid chromatographic methods for the analysis. Free radicals formed from oxygen and its reduction products, nitric oxide, and lipid radicals are considered. Whilst reversed-phase high-performance liquid chromatography has found wide application for these analyses, ion-exclusion chromatography also has significant potential and some developments in this area are described.

Item Type: Article
Keywords: High-performance liquid chromatography; Ion exclusion chromatography; Reactive oxygen species; Free radicals; Nitric oxide; Malonyldialdehyde
Journal or Publication Title: TrAC - Trends in Analytical Chemistry
Page Range: pp. 492-497
ISSN: 0167-2940
Identification Number - DOI: 10.1016/S0165-9936(00)00018-2
Additional Information: The definitive version is available at http://www.sciencedirect.com
Date Deposited: 31 Oct 2008 05:49
Last Modified: 18 Nov 2014 03:52
URI: http://eprints.utas.edu.au/id/eprint/7918
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