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Meniscal tear and increased tibial plateau bone area in healthy post-menopausal women
Davis-Tuck, ML and Martel-Pelletier, J and Wluka, AE and Pelletier, JP and Ding, C and Jones, G and Davis, S and Cicuttini, FM (2008) Meniscal tear and increased tibial plateau bone area in healthy post-menopausal women. Osteoarthritis and Cartilage, 16 (2). pp. 268-271.
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Meniscal tears detected using magnetic resonance imaging (MRI) have been identified as a risk factor for the development and progression of Osteoarthritis, however the prevalence and significance of meniscal tears in healthy, asymptomatic adults remains to be studied. We investigated the prevalence of meniscal tears in a healthy pain free population of post-menopausal women and whether meniscal tears in this population are associated with changes in cartilage volume and defects and tibial plateau bone area over 2 years.This study demonstrates that meniscal tears are common in asymptomatic post-menopausal women and that they become more common with age. Meniscal tears were also associated with greater tibial plateau bone area but not cartilage volume, providing support to the hypothesis that tibial plateau bone changes occur before significant pathological changes in cartilage. Whether increased tibial plateau bone area predisposes to an increased risk of degenerative meniscal tears or whether it is a consequence of altered biomechanical forces in relation to meniscal tear will need to be determined.
|Keywords:||Meniscal tears; Healthy post-menopausal women; Cartilage volume/defect; Bone area|
|Journal or Publication Title:||Osteoarthritis and Cartilage|
|Page Range:||pp. 268-271|
|Identification Number - DOI:||dx.doi.org/10.1016/j.joca.2007.10.018|
|Additional Information:||The definitive version is available at http://www.sciencedirect.com|
|Date Deposited:||29 Jan 2009 03:47|
|Last Modified:||18 Nov 2014 03:55|
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