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Which bone mass measures discriminate adolescents who have fractured from those who have not?
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Summary This study of 415 adolescent children examined
the association between four different measures of bone
mass and prevalent fracture (N=160 children). DXA
measures and calcaneal ultrasound (but not radial ultrasound
or metacarpal index) were associated with upper
limb fracture, suggesting heel ultrasound is also a discriminator
of fractures in children.
Introduction The aim of the study was to describe the
association between different measures of bone mass and
prevalent fracture in adolescents.
Methods A total of 415 adolescents (150 girls and 265
boys), mean age 16.3 years were examined. Dual energy Xray
absorptiometry (DXA) measures were performed at hip,
spine, radius and total body. Calcaneal bone ultrasound
attenuation (BUA), speed of sound (SOS), and stiffness
were assessed by a Sahara densitometer. Radial ultrasound
SOS was assessed by a Sunlight 8000P machine. Metacarpal
index was calculated from a left hand X-ray. Prevalent
fractures were assessed by questionnaire.
Results A total of 160 adolescents (39%) reported at least
one previous fracture (106 upper limb, 53 lower limb, one
other for first fracture). Significantly lower DXA measures,
heel BUA, and heel stiffness was observed in those with a
history of upper limb fracture (all P<0.05). Despite
significant correlations between all the bone mass measures,
radial ultrasound and metacarpal index did not
discriminate those with fracture from those without. Similar associations were present for number of fractures. No bone
measure was able to discriminate lower limb fracture.
Conclusions Both calcaneal quantitative ultrasound and
DXA are able to discriminate adolescents with a history
of upper limb fracture from those without.
|Keywords:||Bone mass . Children . Fracture|
|Journal or Publication Title:||Osteoporosis International|
|Page Range:||pp. 251-255|
|Identification Number - DOI:||10.1007/s00198-007-0458-1|
The original publication is available at www.springerlink.com
|Date Deposited:||06 Mar 2009 01:03|
|Last Modified:||18 Nov 2014 03:56|
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