Decline in Physical Fitness From Childhood to Adulthood Associated With Increased Obesity and Insulin Resistance in Adults
Dwyer, T and Magnussen, CG and Schmidt, MD and Ukoumunne, O and Ponsonby, AL and Raitakari, OT and Zimmet, P and Blair, SN and Thomson, R and Cleland, V and Venn, AJ (2009) Decline in Physical Fitness From Childhood to Adulthood Associated With Increased Obesity and Insulin Resistance in Adults. Diabetes Care, 32 (4). pp. 683-687. ISSN 0149-5992 EISSN: 1935-5548
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Official URL: http://dx.doi.org/10.2337/dc08-1638
OBJECTIVE— To examine how fitness in both childhood and adulthood is associated with adult obesity and insulin resistance.
RESEARCH DESIGN AND METHODS— A prospective cohort study set in Australia in 2004–2006 followed up a cohort of 647 adults who had participated in the Australian Schools
Health and Fitness Survey in 1985 and who had undergone anthropometry and cardiorespiratory fitness assessment during the survey. Outcome measures were insulin resistance and obesity, defined as a homeostasis model assessment index above the 75th sex-specific percentile and
BMI 30 kg/m2, respectively.
RESULTS— Lower levels of child cardiorespiratory fitness were associated with increased odds of adult obesity (adjusted odds ratio [OR] per unit decrease 3.0 [95% CI 1.6 –5.6]) and insulin resistance (1.7 [1.1–2.6]). A decline in fitness level between childhood and adulthood
was associated with increased obesity (4.5 [2.6 –7.7]) and insulin resistance (2.1 [1.5–2.9]) per unit decline.
CONCLUSIONS— A decline in fitness from childhood to adulthood, and by inference a decline in physical activity, is associated with obesity and insulin resistance in adulthood. Programs aimed at maintaining high childhood physical activity levels into adulthood may have potential for reducing the burden of obesity and type 2 diabetes in adults.
|Additional Information:||© 2009 by the American Diabetes Association. |
|Deposited By:||Ms Marita Dalton|
|Deposited On:||13 Jul 2010 14:01|
|Last Modified:||27 Aug 2013 10:52|
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