Library Open Repository

Oral contraceptive use and bone mass in women aged 26–36 years

Downloads

Downloads per month over past year

Wei, S and Jones, G and Thomson, RJ and Dwyer, T and Venn, AJ (2010) Oral contraceptive use and bone mass in women aged 26–36 years. Osteoporosis International, 22 (1). pp. 351-355. ISSN 0937-941X

[img] PDF
Wei_OC_and_bone_2010.pdf | Request a copy
Full text restricted
Available under University of Tasmania Standard License.

Abstract

Introduction: The association between hormonal contraceptive use and bone mineral density remains controversial. Hypothesis Hormonal contraceptive use is positively associated with bone mass in young premenopausal women. Methods: Cross-sectional analysis of data collected from women aged 26–36 years (n=687) in the Childhood Determinants of Adult Health study—a longitudinal study investigating childhood determinants of cardiovascular disease, diabetes, and other chronic diseases in adulthood. Participants were not currently pregnant or breast-feeding. Contraceptive use was obtained by self-administered questionnaire. Women were categorized as combined oral contraceptive users (n=219), progestogen-only contraceptive users (n=43), and non-users of hormonal contraceptives (n= 425). Bone mass was measured by quantitative ultrasound. Results Compared with women who were not using any hormonal contraceptives, women using combined oral contraceptives had significantly higher values of broadband ultrasound attenuation (BUA), speed of sound, and quantitative ultrasound index. These associations remained after adjustment for confounders. Progestogen-only contraceptive users had higher BUA than non-users, but the differences were not statistically significant in this small group. Conclusion: Combined oral contraceptive use was associated with higher bone mass measured by quantitative ultrasound in this population-based sample of premenopausal women aged 26–36 while progestogen-only contraceptives appeared to have no deleterious effect on bone mass.

Item Type: Article
Keywords: Bone mass . Contraceptive . Oral contraceptive . Population . Progestogen . Quantitative ultrasound . Young women
Journal or Publication Title: Osteoporosis International
Page Range: pp. 351-355
ISSN: 0937-941X
Identification Number - DOI: 10.1007/s00198-010-1180-y
Additional Information: The original publication is available at www.springerlink.com
Date Deposited: 16 Jun 2010 04:54
Last Modified: 18 Nov 2014 04:11
URI: http://eprints.utas.edu.au/id/eprint/9881
Item Statistics: View statistics for this item

Repository Staff Only (login required)

Item Control Page Item Control Page