TY - JOUR N1 - restricted - published by Thompson ID - epprod3610 UR - http://www.biomedcentral.com/1472-4472/7?issue=11 IS - 11 A1 - Ding, C Y1 - 2006/// N2 - Vertex Pharmaceuticals Inc, in collaboration with Kissei Pharmaceutical Co Ltd, is developing VX-702, one of a series of second-generation, orally active p38 MAP kinase inhibitors, for the potential treatment of inflammation, rheumatoid arthritis and cardiovascular diseases. In June 2005, a phase II clinical trial of VX-702 was initiated in rheumatoid arthritis. In July 2006, Vertex was planning to file an IND in the second half of 2006. JF - Current Opinion in Investigational Drugs VL - 7 SN - 1472-4472 TI - Drug evaluation: VX-702, a MAP kinase inhibitor for rheumatoid arthritis and acute coronary syndrome SP - 1020 AV - public EP - 1025 ER -