creators_name: Guijt, RM
creators_name: Dodge, A
creators_name: van Dedem, GWK
creators_name: de Rooij, NF
creators_name: Verpoorte, E
creators_id: Rosanne.Guijt@utas.edu.au
creators_id: 
creators_id: 
creators_id: 
creators_id: 
type: article
datestamp: 2008-04-22 06:13:25
lastmod: 2008-07-18 10:52:17
metadata_visibility: show
title: Chemical and physical processes for integrated temperature control in microfluidic devices
ispublished: pub
subjects: 250000
subjects: 250401
subjects: 250400
full_text_status: restricted
note: Copyright 2003, The Royal Society of Chemistry.
abstract: Microfluidic devices are a promising new tool for studying and optimizing (bio)chemical reactions and analyses. Many (bio)chemical reactions require accurate temperature control, such as for example thermocycling for PCR. Here, a new integrated temperature control system for microfluidic devices is presented, using chemical and physical processes to locally regulate temperature. In demonstration experiments, the evaporation of acetone was used as an endothermic process to cool a microchannel. Additionally, heating of a microchannel was achieved by dissolution of concentrated sulfuric acid in water as an exothermic process. Localization of the contact area of two flows in a microfluidic channel allows control of the position and the magnitude of the thermal effect.
date: 2003-02
date_type: published
publication: Lab on a Chip
volume: 3
number: 1
pagerange: 1-4
id_number: 10.1039/b210629a
refereed: TRUE
issn: print 1473-0197; online 1473-0189
official_url: http://dx.doi.org/10.1039/b210629a
related_url_url: http://www.rsc.org/Publishing/Journals/LC/
related_url_type: pub
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citation: Guijt, RM and Dodge, A and van Dedem, GWK and de Rooij, NF and Verpoorte, E (2003) Chemical and physical processes for integrated temperature control in microfluidic devices. Lab on a Chip, 3 (1). pp. 1-4. ISSN print 1473-0197; online 1473-0189
document_url: http://eprints.utas.edu.au/6138/1/RMG10.pdf