Please Note:

The Open Access Repository has moved to a new authentication system as of the 1st of November.

Account holders will now be able to login using their University of Tasmania credentials.
If you have trouble logging in please email us on E.Prints@utas.edu.au so we can assist you.

Public users can still access the records in this repository as normal

Open Access Repository

Genetic association between GHSR1a 5′UTR-microsatellite and nt-7(C>A) loci and growth and carcass traits in Japanese Black cattle

Komatsu, M and Itoh, T and Fujimori, Y and Satoh, M and Miyazaki, Y and Takahashi, H and Shimizu, K and Malau-Aduli, AEO and Morita, M (2011) Genetic association between GHSR1a 5′UTR-microsatellite and nt-7(C>A) loci and growth and carcass traits in Japanese Black cattle. Animal Science Journal, 82 (3). pp. 396-405. ISSN 1740-0929

[img] PDF
Komatsu_et_al_2...pdf | Request a copy
Full text restricted
Available under University of Tasmania Standard License.

[img] PDF (Author Version)
Komatsu_et_al_2...pdf | Request a copy
Full text restricted
Available under University of Tasmania Standard License.

[img] PDF (Diagram)
Komatsu_et_al_2...pdf | Request a copy
Full text restricted
Available under University of Tasmania Standard License.

[img] PDF (Table)
Komatsu_et_al_2...pdf | Request a copy
Full text restricted
Available under University of Tasmania Standard License.

[img] PDF (Table)
Komatsu_et_al_2...pdf | Request a copy
Full text restricted
Available under University of Tasmania Standard License.

[img] PDF (Table)
Komatsu_et_al_2...pdf | Request a copy
Full text restricted
Available under University of Tasmania Standard License.

[img] PDF (Table)
Komatsu_et_al_2...pdf | Request a copy
Full text restricted
Available under University of Tasmania Standard License.

[img] PDF (Table)
Komatsu_et_al_2...pdf | Request a copy
Full text restricted
Available under University of Tasmania Standard License.

[img] PDF (Table)
Komatsu_et_al_2...pdf | Request a copy
Full text restricted
Available under University of Tasmania Standard License.

[img] PDF (Table)
Komatsu_et_al_2...pdf | Request a copy
Full text restricted
Available under University of Tasmania Standard License.

Abstract

We carried out a genetic association study between five nucleotide polymorphisms (5′UTR microsatellite ((TG)n), nt-7(C>A), L24V, DelR242 and Intron 1 microsatellite) of the GHSR1a gene and growth and carcass traits in 1285 steers sired by 117 Japanese Black bulls in a progeny testing program. We report herein, a significant association between the 5′UTR microsatellite and nt-7(C>A) loci and growth and carcass traits. We also propose a translational hypothesis that the association is due to differences in the secondary structure of GHSR1b mRNA (the non-spliced type with the 5′UTR microsatellite) among the GHSR1a gene haplotypes. Furthermore, we predicted the potential increase in profitability due to increased carcass weight in cow-calf fattening enterprises through planned matings based on DNA testing of the 5′UTR microsatellite. Statistical analysis revealed that the 5′UTR microsatellite locus had a significant additive effect on carcass weight (CW) and average daily gain (ADG), but not on beef marbling score (BMS). One of the four major microsatellite alleles (19-TG allele) with an allele frequency of 0.145, had a significantly (P < 0.0007) desirable effect on CW and ADG. We concluded that the 19-TG allele could potentially be economically useful nucleotide markers for growth and carcass traits in Japanese Black cattle.

Item Type: Article
Keywords: GHSR, 5’UTR-microsatellite, mRNA secondary structure, growth and carcass traits, Japanese Black cattle
Journal or Publication Title: Animal Science Journal
Page Range: pp. 396-405
ISSN: 1740-0929
Identification Number - DOI: 10.1111/j.1740-0929.2010.00852.x
Additional Information:

The definitive published version is available online at: http://onlinelibrary.wiley.com/

Date Deposited: 21 Jun 2011 00:25
Last Modified: 18 Nov 2014 04:18
Item Statistics: View statistics for this item

Actions (login required)

Item Control Page Item Control Page
TOP