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Cytochromes P450 in gibberellin biosynthesis


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Davidson, SE, Reid, JB and Helliwell, CA 2006 , 'Cytochromes P450 in gibberellin biosynthesis' , Phytochemistry Reviews, vol. 5 , pp. 405-419 , doi: 10.1007/s11101-006-9005-5.

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The gibberellins (GAs) are an important
class of plant growth regulators that are
active in many aspects of plant growth and
development. GAs are synthesized by a complex
pathway involving three enzyme classes spanning
different subcellular compartments. One of these
enzyme classes is the cytochrome P450s which
catalyze a number of oxidation steps in the middle
part of the pathway. Mutants in these cytochrome
P450-mediated steps in a number of
species have been crucial in isolating the genes
encoding these enzymes and have also played an
important role in understanding GA physiology.
GAs are also synthesized by fungi, in a biosynthesis
pathway largely catalyzed by cytochrome
P450s. The fungal pathway appears to have
evolved independently to that of higher plants.

Item Type: Article
Authors/Creators:Davidson, SE and Reid, JB and Helliwell, CA
Journal or Publication Title: Phytochemistry Reviews
ISSN: 1568-7767
DOI / ID Number: 10.1007/s11101-006-9005-5
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