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Abstract

Alkaloid-bearing plants of the Australian Monimiaceae have
generally yielded alkaloids of the bisbenzylisoquinoline type.
For this reason a brief outline of the chemistry of this class of
compound will be presented; a more detailed account may be found in
a complete and thorough review by Grundon 1.
The bisbenzylisoquinoline molecule consists of two benzylisoquinoline
moieties linked by one, two or three oxygen atoms;
these ether bridges are believed to arise by intermolecular dehydrogenation
of two molecules of 1-(4-hydroxybenzy1)-6,7-dehydroxy-1,2,3,
4-tetrahydroisoquinoline in which the new C-0 bond is formed by
phenolic coupling at nuclear positions ortho to hydroxyl groups.
The route which the dehydrogenation follows leads to the classification
of bisbenzylisoquinoline alkaloids into several different
classes.

Item Type:	Thesis - PhD
Authors/Creators:	Douglas, Gordon Keith
Keywords:	Alkaloids, Monimiaceae
Copyright Holders:	The Author
Copyright Information:	Copyright 1965 the Author - The University is continuing to endeavour to trace the copyright owner(s) and in the meantime this item has been reproduced here in good faith. We would be pleased to hear from the copyright owner(s).
Additional Information:	Thesis (Ph.D.) - University of Tasmania, 1966. Includes bibliography
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