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Early relapse treatment (ERT) or “maintenance” transcranial magnetic stimulation (TMS)?


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Pridmore, S ORCID: 0000-0002-9170-1798, Erger, S, Rybak, M, Kelly, E and Lawson, F 2017 , 'Early relapse treatment (ERT) or “maintenance” transcranial magnetic stimulation (TMS)?' , American Journal of Medical Research, vol. 4, no. 1 , pp. 111-117 .

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Background: Major depressive disorder (MDD) commonly takes arelapsing form. Transcranial magnetic stimulation (TMS) has be suggested as ameans of maintaining remission. Brief courses of TMS at about monthly intervalsappear to provide health benefits. Objective: To examine whether such brief coursesof TMS are better conceptualized as maintaining remission, or as the provision ofearly relapse treatment. Method: 25 series of treatment (18 different patients) wereconsidered. Pre- and post-treatment 6-item Hamilton Depression Rating Scale(HAMD6) and 7 visual analogue scales (VASs) were collected, along with pretreatmentClinical Global Impression-Severity (CGI-S) and post-treatment CGIImprovement(I). Results: Pre-treatment HAMD6 and CGI-S indicated that manypatients were symptomatic and in early relapse. Post-treatment HAMD6 indicatedthat many patients had achieved remission, and this was supported by the CGI-I. The VAS scores also improved. Conclusions: Short courses of TMS at about monthlyintervals have beneficial results and are better conceptualized as early relapsetreatment (ERT).

Item Type: Article
Authors/Creators:Pridmore, S and Erger, S and Rybak, M and Kelly, E and Lawson, F
Keywords: major depressive disorder; transcranial magnetic stimulation; early relapse treatment
Journal or Publication Title: American Journal of Medical Research
Publisher: Addleton Academic Publishers
ISSN: 2334-4814
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© 2009 Addleton Academic Publishers. All Rights Reserved.

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