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Vitamin D deficiency in joint pain: Effects of vitamin D supplementation

Antony, B ORCID: 0000-0001-8704-6084 and Ding, C ORCID: 0000-0002-9479-730X 2017 , 'Vitamin D deficiency in joint pain: Effects of vitamin D supplementation', in RR Watson and S Zibadi (eds.), Nutritional Modulators of Pain in the Aging Population , Academic Press, United States, pp. 183-189.

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Objective: This chapter reviews the evidence of the role of vitamin D deficiency in joint pain and the effects of vitamin D supplementation on joint pain. Results: There are inconsistent results from the observational studies that explored the association between vitamin D deficiency and joint pain relating to major musculoskeletal conditions. Some reported a weak, but statistically significant association with knee and hip joint pain and the association was apparent only in people with moderate vitamin D deficiency.There are only a few randomized placebo-controlled trials that have explored the effect of vitamin D supplementation on joint pain. The available evidence suggests that there is no clinically significant benefit of vitamin D supplementation for knee pain. The nonrandomized clinical trials reported a small beneficial effect on joint pain. Conclusion: The available evidence suggests that vitamin D supplementation may not have a significant effect on the management of joint pain.

Item Type: Book Section
Authors/Creators:Antony, B and Ding, C
Keywords: vitamin D deficiency, joint pain, knee, hip, supplementation, musculoskeletal pain, osteoarthritis, rheumatoid arthritis
Publisher: Academic Press
DOI / ID Number: 10.1016/B978-0-12-805186-3.00015-1
Copyright Information:

Copyright 2017 Elsevier Inc.

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