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Automated cell culture systems and their applications to human pluripotent stem cell studies

Daniszewski, M, Crombie, DE, Henderson, R, Liang, HH, Wong, RCB, Hewitt, AW ORCID: 0000-0002-5123-5999 and Pebay, A 2017 , 'Automated cell culture systems and their applications to human pluripotent stem cell studies' , SLAS Technology , pp. 1-11 , doi: 10.1177/2472630317712220.

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Abstract

Pluripotent stem cells are an extremely powerful tool in modeling human diseases and hold much promise for personalized regenerative or cell replacement therapies. There is an increasing need for reproducible large-scale stem cell and differentiated progeny production, with minimal variation, rendering manual approaches impracticable. Here, we provide an overview of systems currently available for automated stem cell culture, and undertake a review of their capacities, capabilities, and relative limitations. With the merging of modern technology and stem cell biology, an increased demand and implementation of automated platforms for stem cell studies is anticipated.

Item Type: Article
Authors/Creators:Daniszewski, M and Crombie, DE and Henderson, R and Liang, HH and Wong, RCB and Hewitt, AW and Pebay, A
Keywords: automated stem cell system, automation, differentiation, embryonic stem cells, induced pluripotent stem cells, passaging
Journal or Publication Title: SLAS Technology
Publisher: Sage Publications, Inc.
ISSN: 2472-6303
DOI / ID Number: 10.1177/2472630317712220
Copyright Information:

© 2017 Society for Laboratory Automation and Screening

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