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Infection of the fittest: devil facial tumour disease has greatest effect on individuals with highest reproductive output

Wells, K, Hamede, RK ORCID: 0000-0003-1526-225X, Kerlin, DH, Storfer, A, Hohenlohe, PA, Jones, ME ORCID: 0000-0001-7558-9022 and McCallum, HI 2017 , 'Infection of the fittest: devil facial tumour disease has greatest effect on individuals with highest reproductive output' , Ecology Letters, vol. 20, no. 6 , pp. 770-778 , doi: 10.1111/ele.12776.

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Abstract

Emerging infectious diseases rarely affect all members of a population equally and determining how individuals’ susceptibility to infection is related to other components of their fitness is critical to understanding disease impacts at a population level and for predicting evolutionary trajectories. We introduce a novel state-space model framework to investigate survival and fecundity of Tasmanian devils (Sarcophilus harrisii) affected by a transmissible cancer, devil facial tumour disease. We show that those devils that become host to tumours have otherwise greater fitness, with higher survival and fecundity rates prior to disease-induced death than non-host individuals that do not become infected, although high tumour loads lead to high mortality. Our finding that individuals with the greatest reproductive value are those most affected by the cancer demonstrates the need to quantify both survival and fecundity in context of disease progression for understanding the impact of disease on wildlife populations.

Item Type: Article
Authors/Creators:Wells, K and Hamede, RK and Kerlin, DH and Storfer, A and Hohenlohe, PA and Jones, ME and McCallum, HI
Keywords: Bayesian capture-recapture, disease burden, disease progression, disease risk, fecundity, individual fitness, pathogenesis, transmissible cancer, tumour growth
Journal or Publication Title: Ecology Letters
Publisher: Wiley-Blackwell Publishing Ltd.
ISSN: 1461-0248
DOI / ID Number: 10.1111/ele.12776
Copyright Information:

© 2017 John Wiley & Sons

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