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A review of caffeine use as a risk or protective factor for women’s health and pregnancy

Peacock, A ORCID: 0000-0002-5705-2026, Mattick, RP and Bruno, R ORCID: 0000-0001-6673-833X 2017 , 'A review of caffeine use as a risk or protective factor for women’s health and pregnancy' , Current opinion in psychiatry, vol. 30, no. 4 , pp. 1-7 , doi: 10.1097/YCO.0000000000000333.

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Purpose of review:To provide a narrative synthesis of recently published studies on caffeine use as a risk or protective factorfor health outcomes, with a focus on women’s health and pregnancy.Recent findings:Based on predominantly observational studies, moderate caffeine intake has been shown to be a protectivefactor for liver cancer, certain bowel conditions, colorectal cancer, skin cancer, and regular menstrualcycle function. However, heavy consumption is a risk factor for osteoporosis, urinary incontinence, andpoorer birth and child developmental outcomes. Residual confounding and issues surrounding retrospectiveself-reported intake are cited as key limitations in the majority of these studies. Moderate caffeine intakehas been associated with lower risk of cardiovascular disease and metabolic syndrome; however, recentgenetic epidemiology studies provide no evidence for a causal relationship.Summary:Greater inclusion of female participants in studies, and analysis of sex differences in the relationshipbetween caffeine intake and certain health conditions, is necessary. The current literature suggestscaffeine’s role as a risk or protective factor differs across health conditions. Often, there are plausiblebiological mechanisms for this relationship. However, a continued precautionary stance is recommendeduntil direct causal pathways are established. Review of recently published studies does not suggest thatcurrent intake guidelines for adults and for pregnant woman need to be modified.

Item Type: Article
Authors/Creators:Peacock, A and Mattick, RP and Bruno, R
Keywords: birth outcomes, caffeine, health, pregnancy, women
Journal or Publication Title: Current opinion in psychiatry
Publisher: Lippincott Williams & Wilkins
ISSN: 0951-7367
DOI / ID Number: 10.1097/YCO.0000000000000333
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Copyright 2017 Wolters Kluwer Health, Inc. All rights reserved.

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