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Abstract

Background: Long-term publicly waitlisted bariatric surgerypatients typically experience debilitating physical/psychosocial obesity-related comorbidities that profoundlyaffect their quality of life.Objectives: We sought to measure quality-of-life impactsin a study population of severely obese patients who hadmultiyear waitlist times and then underwent bariatricsurgery.Methods: Participants were recruited opportunistically followinga government-funded initiative to provide bariatricsurgery to morbidly obese long-term waitlisted patients.Participants self-completed the EQ-5D-5L and AQoL-8Dquestionnaires pre- and postoperatively. Utility valuations(utilities) and individual/super dimension scores (AQoL-8D only) were generated.Results: Participants’ (n = 23) waitlisted time was mean[standard deviation (SD)] 6.5 (2) years, body mass indexreduced from 49.3 (9.35) kg/m2 preoperatively to 40.8(7.01) 1 year postoperatively (p = 0.02). One year utilitiesrevealed clinical improvements (both instruments).AQoL-8D improved significantly from baseline to1 year, with the change twice that of the EQ-5D-5L[EQ-5D-5L: mean (SD) 0.70 (0.25) to 0.78 (0.25);AQoL-8D: 0.51 (0.24) to 0.67 (0.23), p = 0.04], despitethe AQoL-8D’s narrower algorithmic range. EQ-5D-5Lutility plateaued from 3 months to 1 year. AQoL-8D1-year utility improvements were driven by Happiness/Coping/Self-worth (p p Conclusions: Ongoing improvements in psychosocialparameters from 3 months to 1 year post-surgeryaccounted for improvements in overall utilities measuredby the AQoL-8D that were not detected by EQ-5D-5L. Selection of a sensitive instrument is importantto adequately assess changes in quality of life and toaccurately reflect changes in quality-adjusted life-yearsfor cost-utility analyses and resource allocation in apublic healthcare resource-constrained environment.

Item Type:	Article
Authors/Creators:	Campbell, JA and Hensher, M and Neil, A and Venn, A and Wilkinson, S and Palmer, AJ
Keywords:	health-related quality of life, bariatric surgery, long-term waitlisted, AQoL-8D, EQ-5D
Journal or Publication Title:	PharmacoEconomics - Open
Publisher:	Adis International Ltd.
ISSN:	2509-4254
DOI / ID Number:	10.1007/s41669-017-0038-z
Copyright Information:	Copyright 2017 The Author(s). Licensed under Creative Commons Attribution-NonCommercial 4.0 International (CC BY-NC 4.0) https://creativecommons.org/licenses/by-nc/4.0/
Related URLs:	Google Scholar: Neil, A UTAS Profile: Neil, A Google Scholar: Venn, A UTAS Profile: Venn, A UTAS Profile: Palmer, AJ
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