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Cancer is not (only) a senescence problem

Thomas, F, Vavre, F, Tissot, T, Vittecoq, M, Giraudeau, M, Bernex, F, Misse, D, Renaud, F, Raven, N, Beckmann, C, Hamede, R ORCID: 0000-0003-1526-225X, Biro, PA and Ujvari, B 2018 , 'Cancer is not (only) a senescence problem' , Trends in Cancer, vol. 4, no. 3 , pp. 169-172 , doi:

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Age is one of the strongest predictors of cancer and risk of death from cancer. Cancer is therefore generally viewed as a senescence-related malady. However, cancer also exists at subclinical levels in humans and other animals, but its earlier effects on the body are poorly known by comparison. We argue here that cancer is a significant but ignored burden on the body and is likely to be a strong selective force from early during the lifetime of an organism. It is time to adopt this novel view of malignant pathologies to improve our understanding of the ways in which oncogenic phenomena influence the ecology and evolution of animals long before their negative impacts become evident and fatal.

Item Type: Article
Authors/Creators:Thomas, F and Vavre, F and Tissot, T and Vittecoq, M and Giraudeau, M and Bernex, F and Misse, D and Renaud, F and Raven, N and Beckmann, C and Hamede, R and Biro, PA and Ujvari, B
Keywords: cancer, ecology, evolution
Journal or Publication Title: Trends in Cancer
Publisher: Cell Press
ISSN: 2405-8033
DOI / ID Number:
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Copyright 2018 Elsevier Ltd.

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