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The combination of exercise training and Zataria multiflora supplementation increase serum irisin levels in postmenopausal women


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Ghanbari-Niaki, A, Saeidi, A, Ahmadian, M, Gharahcholo, L, Naghavi, N, Fazelzadeh, M, Mahjoub, S, Myers, S ORCID: 0000-0003-4793-3820 and Williams, A ORCID: 0000-0001-8863-3491 2018 , 'The combination of exercise training and Zataria multiflora supplementation increase serum irisin levels in postmenopausal women' , Integrative Medicine Research, vol. 7 , pp. 44-52 , doi: 10.1016/j.imr.2018.01.007.

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Background:We examined the effect of antioxidant supplementation and exercise on irisin within postmenopausal women.Methods:Forty-eight participants (age: 55.7 ± 4.9 years; weight: 68.0 ± 6.3 kg; BMI 27.0 ± 2.7; mean ± SD) were randomized into four groups for the eight week intervention: control group (CG; n = 12), resistance training group (RTG; n = 12), supplementation with Zataria multiflora group (ZG; n = 12), or supplementation with Z. multiflora and resistance training group (ZRTG; n = 12). RTG and ZRTG performed circuit resistance training, and both ZG and ZRTG consumed 500 mg of Z. multifloraevery day during the intervention. Blood samples were taken 48 hours before and after the intervention.Results:There was a significant difference in irisin at post-training, with greater levels in ZRTG compared to CG. A significant increase was noted for irisin at post-training compared to pre-training for ZG, RTG, and ZRTG. Moreover, we identified a significant decrease in malondialdehyde in the RTG and ZRTG groups and increase in glutathione in the ZG, RTG, and ZRTG groups when compared to CG.Conclusion:These findings showed that exercise, Z. multiflora supplementation or their combination led to an increase in irisin.

Item Type: Article
Authors/Creators:Ghanbari-Niaki, A and Saeidi, A and Ahmadian, M and Gharahcholo, L and Naghavi, N and Fazelzadeh, M and Mahjoub, S and Myers, S and Williams, A
Keywords: Irisin, antioxidants, Exericise
Journal or Publication Title: Integrative Medicine Research
Publisher: Elsevier BV
ISSN: 2213-4220
DOI / ID Number: 10.1016/j.imr.2018.01.007
Copyright Information:

Copyright 2018 Korea Institute of Oriental MedicineLicensed under Creative Commons Attribution-NonCommercial-NoDerivatives 4.0 International (CC BY-NC-ND 4.0)

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