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Methods for the synthesis of annulated pyrroles via cyclisation strategies

Olivier, WJ, Smith, JA ORCID: 0000-0001-6313-3298 and Bissember, AC ORCID: 0000-0001-5515-2878 2018 , 'Methods for the synthesis of annulated pyrroles via cyclisation strategies' , Organic and Biomolecular Chemistry, vol. 16, no. 8 , pp. 1216-1226 , doi: 10.1039/C7OB03144K.

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Abstract

Pyrrole, pyrrolidine, and indolizidine alkaloids represent important classes of natural products. Historically, these heterocycles and their derivatives have been the focus of significant interest in organic synthesis. In this report, we review the methods that have been employed to synthesise annulated pyrroles via transformations that include: Friedel–Crafts acylations and alkylations, Michael additions, Heck couplings, hydroarylations, carbenoid insertions, and radical cyclisations.

Item Type: Article
Authors/Creators:Olivier, WJ and Smith, JA and Bissember, AC
Keywords: pyrrole, organic synthesis, methodology, heterocyclic chemistry
Journal or Publication Title: Organic and Biomolecular Chemistry
Publisher: Royal Soc Chemistry
ISSN: 1477-0520
DOI / ID Number: 10.1039/C7OB03144K
Copyright Information:

© The Royal Society of Chemistry 2018

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