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Provenance and risk in transfer of biological materials

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Nielsen, J ORCID: 0000-0002-3005-0047, Bubela, T, Chalmers, DRC ORCID: 0000-0002-7925-8818, Johns, A, Kahl, L, Kames, J, Lawson, C, McWhirter, R ORCID: 0000-0002-9409-8074, Monotti, A, Scheibner, JK ORCID: 0000-0003-3667-398X, Whitton, T and Nicol, D ORCID: 0000-0002-6553-2839 2018 , 'Provenance and risk in transfer of biological materials' , PLOS Biology, vol. 16, no. 8 , pp. 1-9 , doi: 10.1371/journal.pbio.2006031.

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Abstract

Whereas biological materials were once transferred freely, there has been a marked shift in the formalisation of exchanges involving these materials, primarily through the use of Material Transfer Agreements (MTAs). This paper considers how risk aversion dominates MTA negotiations and the impact it may have on scientific progress. Risk aversion is often based on unwarranted fears of incurring liability through the use of a material or loss of control or missing out on commercialisation opportunities. Evidence to date has suggested that complexity tends to permeate even straightforward transactions despite extensive efforts to implement simple, standard MTAs. We argue that in most cases, MTAs need do little more than establish provenance, and any attempt to extend MTAs beyond this simple function constitutes stifling behaviour. Drawing on available examples of favourable practice, we point to a number of strategies that may usefully be employed to reduce risk-averse tendencies, including the promotion of simplicity, education of those engaged in the MTA process, and achieving a cultural shift in the way in which technology transfer office (TTO) success is measured in institutions employing MTAs.

Item Type: Article
Authors/Creators:Nielsen, J and Bubela, T and Chalmers, DRC and Johns, A and Kahl, L and Kames, J and Lawson, C and McWhirter, R and Monotti, A and Scheibner, JK and Whitton, T and Nicol, D
Keywords: material transfer agreement, provenance, risk, biological materials
Journal or Publication Title: PLOS Biology
Publisher: Public Library of Science
ISSN: 1544-9173
DOI / ID Number: 10.1371/journal.pbio.2006031
Copyright Information:

Copyright 2018 The AuthorsLicensed under Creative Commons Attribution 4.0 International (CC BY 4.0)https://creativecommons.org/licenses/by/4.0/

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