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Lifestyle factors and multiple sclerosis: A population-based incident case-control study

Abdollahpour, I, Nedjat, S, Mansournia, MA, Sahraian, MA and van der Mei, I ORCID: 0000-0001-9009-7472 2018 , 'Lifestyle factors and multiple sclerosis: A population-based incident case-control study' , Multiple Sclerosis and Related Disorders, vol. 22 , pp. 128-133 , doi: 10.1016/j.msard.2018.03.022.

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Abstract

Objective: Although low sun exposure, low vitamin D, and smoking are established risk factor of multiple sclerosis (MS), there is less evidence on the role of the other lifestyle factors. We examined the association of sun exposure, physical activity, drug abuse, and alcohol intake with MS.Materials and Methods: This was population-based incident case-control study in Iran with 547 incident cases and 1057 general population controls (7/8/2013-17/2/2015). Logistic regression was used to analyse the data.Results: Higher sun exposure during adolescence was associated with a reduced risk of MS, both in summer (test for trend p Conclusion: In a middle-eastern setting, we found that sun exposure during adolescence, drug abuse, and alcohol use were all associated with MS. Increasing sun exposure and reducing drug abuse and the use of alcohol through educational programs is likely to reduce the rate of MS.

Item Type: Article
Authors/Creators:Abdollahpour, I and Nedjat, S and Mansournia, MA and Sahraian, MA and van der Mei, I
Keywords: alcohol, case-control, drug abuse, lifestyle factors, multiple sclerosis, physical activity, sun exposure
Journal or Publication Title: Multiple Sclerosis and Related Disorders
Publisher: Elsevier BV
ISSN: 2211-0348
DOI / ID Number: 10.1016/j.msard.2018.03.022
Copyright Information:

Copyright 2018 Published by Elsevier B.V.

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