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Metal-organic framework mixed-matrix disks: versatile supports for automated solid-phase extraction prior to chromatographic separation

Ghani, M, Pico, MFF, Salehinia, S, Cabello, CP, Maya, F ORCID: 0000-0003-1458-736X, Berlier, G, Saraji, M, Cerda, V and Palomino, GT 2017 , 'Metal-organic framework mixed-matrix disks: versatile supports for automated solid-phase extraction prior to chromatographic separation' , Journal of Chromatography A, vol. 1488 , pp. 1-9 , doi: 10.1016/j.chroma.2017.01.069.

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We present for the first time the application of metal-organic framework (MOF) mixed-matrix disks (MMD) for the automated flow-through solid-phase extraction (SPE) of environmental pollutants. Zirconium terephthalate UiO-66 and UiO-66-NH2 MOFs with different size (90, 200 and 300 nm) have been incorporated into mechanically stable polyvinylidene difluoride (PVDF) disks. The performance of the MOF-MMDs for automated SPE of seven substituted phenols prior to HPLC analysis has been evaluated using the sequential injection analysis technique. MOF-MMDs enabled the simultaneous extraction of phenols with the concomitant size exclusion of molecules of larger size. The best extraction performance was obtained using a MOF-MMD containing 90 nm UiO-66-NH2 crystals. Using the selected MOF-MMD, detection limits ranging from 0.1 to 0.2 μg L−1 were obtained. Relative standard deviations ranged from 3.9 to 5.3% intra-day, and 4.7–5.7% inter-day. Membrane batch-to-batch reproducibility was from 5.2 to 6.4%. Three different groundwater samples were analyzed with the proposed method using MOF-MMDs, obtaining recoveries ranging from 90 to 98% for all tested analytes.

Item Type: Article
Authors/Creators:Ghani, M and Pico, MFF and Salehinia, S and Cabello, CP and Maya, F and Berlier, G and Saraji, M and Cerda, V and Palomino, GT
Keywords: membranes, chromatography, metal-organic frameworks, mixed-matrix disks, solid-phase extraction, sequential injection analysis, high performance liquid chromatography, phenols
Journal or Publication Title: Journal of Chromatography A
Publisher: Elsevier Science Bv
ISSN: 0021-9673
DOI / ID Number: 10.1016/j.chroma.2017.01.069
Copyright Information:

© 2017 Elsevier B.V. All rights reserved.

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