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Data on prolonged morphine-induced antinociception and behavioral inhibition in older rats


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Paul, AK ORCID: 0000-0002-6090-2407, Gueven, N ORCID: 0000-0003-3782-767X and Dietis, N ORCID: 0000-0002-8365-3837 2018 , 'Data on prolonged morphine-induced antinociception and behavioral inhibition in older rats' , Data in Brief, vol. 19 , pp. 183-188 , doi: 10.1016/j.dib.2018.05.001.

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This article contains supportive data related to a research article entitled "Age-dependent antinociception and behavioral inhibition by morphine" (Paul et al., 2018) [1]. Antinociceptive latencies of 8 and 24-week old rats were obtained from tail-flick and hot plate assays after morphine treatment. Motor behavioral effects were measured at different time-points using automated infrared tracking in an open-field arena. Residual morphine content in post-mortem tissues were measured 240 min post-treatment. Concurrent measurements of antinociception, motor behavior and residual morphine content in post-mortem tissues of 8-week and 24-week old morphine-treated rats provide an integrated assessment of age-related differences.

Item Type: Article
Authors/Creators:Paul, AK and Gueven, N and Dietis, N
Keywords: morphine
Journal or Publication Title: Data in Brief
Publisher: Elsevier B.V.
ISSN: 2352-3409
DOI / ID Number: 10.1016/j.dib.2018.05.001
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Copyright 2018 the authors. Licensed under Creative Commons Attribution 4.0 International (CC BY 4.0)

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