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Deprescribing medications in older people: a narrative review

Salahudeen, MS ORCID: 0000-0001-9131-7465 2018 , 'Deprescribing medications in older people: a narrative review' , Drugs of Today, vol. 54, no. 8 , pp. 489-498 , doi:

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In the aging population, the process of medicationprescribing and management is likely to be complexand challenging. Polypharmacy and inappropriatemedication use are more prevalent among olderpeople and are associated with geriatric syndromes,reduced cognitive and functional outcomes, andincreased mortality. Deprescribing is the process ofplanned and supervised tapering or safe withdrawalof potentially inappropriate medication that cancause harm, or is no longer indicated or beneficial tothe current therapy. The purpose of deprescribing is toreduce inappropriate polypharmacy, medication burdenand harm, and to improve patient health-relatedoutcomes. Deprescribing is best performed by reducingmedicines one at a time, and the whole processrequires careful assessment, effort, commitment andtime. Deprescribing should be considered after carefulassessment of the patient’s overall health, therapeuticgoals, medication adherence to current treatmentregimen and willingness to deprescribe the medicine.Many medications can be safely removed; to successfullyachieve this, the process of deprescribingshould follow an evidence-based, patient-centeredand team-based approach involving both the healthcareprofessionals and the patient/caregivers to effectivelyreduce inappropriate medication use.

Item Type: Article
Authors/Creators:Salahudeen, MS
Keywords: deprescribing; elderly
Journal or Publication Title: Drugs of Today
Publisher: Prous Science
ISSN: 1699-3993
DOI / ID Number:
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Copyright 2018 Clarivate Analytics

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