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Youth and long-term dietary calcium intake with risk of impaired glucose metabolism and type 2 diabetes in adulthood
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Abstract
Context: No previous studies have examined the role of youth calcium intake in the development of impaired glucose metabolism, particularly those with long-term high calcium intake.Objectives: To examine whether youth and long-term (between youth and adulthood) dietary calcium intake is associated with adult impaired glucose metabolism and T2D.Design, Setting, and Participants: The Cardiovascular Risk in Young Finns Study (YFS) is a 31-year prospective cohort study (n=1134, aged 3-18 years at baseline).Exposures: Dietary calcium intake was assessed at baseline (1980) and adult follow-ups (2001, 2007 and 2011). Long-term (mean between youth and adulthood) dietary calcium intake was calculated.Main outcome measures: Adult impaired fasting glucose (IFG) and T2D.Results: We found no evidence for non-linear associations between calcium intake with IFG or T2D among females and males (all p for non-linearity>0.05). Higher youth and long-term dietary calcium intake was not associated with the risk of IFG or T2D among females or males after adjustment for confounders including youth and adult BMI.Conclusions: Youth or long-term dietary calcium intake is not associated with adult risk of developing impaired glucose metabolism or T2D.
Item Type: | Article |
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Authors/Creators: | Wu, F and Juonala, M and Pahkala, K and Buscot, MJ and Sabin, MA and Pitkanen, N and Ronnemaa, T and Jula, A and Lehtimaki, T and Hutri-Kahonen, N and Kahonen, M and Laitinen, T and Viikari, JSA and Raitakari, OT and Magnussen, CG |
Journal or Publication Title: | Journal of Clinical Endocrinology and Metabolism |
Publisher: | Endocrine Soc |
ISSN: | 0021-972X |
DOI / ID Number: | 10.1210/jc.2018-02321 |
Copyright Information: | Copyright 2019 Endocrine Society |
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