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Relation of blood pressure in childhood to self-reported hypertension in adulthood: The International Childhood Cardiovascular Cohort Consortium

Urbina, EM, Khoury, PR, Bazzano, L, Burns, TL, Daniels, S, Dwyer, T, Hu, T, Jacobs Jr, DR, Juonala, M, Prineas, R, Raitakari, O, Steinberger, J, Venn, A ORCID: 0000-0001-7090-1398, Woo, JG and Sinaiko, A 2019 , 'Relation of blood pressure in childhood to self-reported hypertension in adulthood: The International Childhood Cardiovascular Cohort Consortium' , Hypertension, vol. 73, no. 6 , pp. 1224-1230 , doi: https://doi.org/10.1161/HYPERTENSIONAHA.118.12334.

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Abstract

Blood pressure (BP) tracking (maintaining a BP percentile) across life is not well defined but is important in predicting which children will become hypertensive adults. We computed BP tracking in subjects with BP measured in childhood and adulthood and performed logistic regression to determine the ability of childhood BP to predict adult hypertension (N=5035, 46.7 years, 74.2% white, 17.7% black; 39.6% male). Prevalence of hypertension was 29%. Correlations between systolic BP for child and adolescent were r=0.48; for adolescent and young adult were r=0.40, and for child and young adult were r=0.24 (all PPP2<0.0001) from 19% in children with a systolic BP% persistently below the median to 80% for individuals with elevated BP in both childhood and adolescence. Although our precision to predict which individual child is at risk of adult BP-related cardiovascular disease is weak, an increase in systolic BP and body mass index percentile from childhood to adolescence should signal a need for lifestyle intervention to prevent future sustained hypertension-related cardiovascular disease.

Item Type: Article
Authors/Creators:Urbina, EM and Khoury, PR and Bazzano, L and Burns, TL and Daniels, S and Dwyer, T and Hu, T and Jacobs Jr, DR and Juonala, M and Prineas, R and Raitakari, O and Steinberger, J and Venn, A and Woo, JG and Sinaiko, A
Keywords: adiposity, blood pressure, hypertension, obesity, risk factor
Journal or Publication Title: Hypertension
Publisher: Lippincott Williams & Wilkins
ISSN: 0194-911X
DOI / ID Number: https://doi.org/10.1161/HYPERTENSIONAHA.118.12334
Copyright Information:

Copyright 2019 American Heart Association, Inc.

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