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Comparison of two-dimensional strain analysis using vendor-independent and vendor-specific software in adult and pediatric patients

Anwar, S, Negishi, K ORCID: 0000-0002-9086-2565, Borowszki, A, Gladding, P, Popovic, ZB, Erenberg, F and Thomas, JD 2017 , 'Comparison of two-dimensional strain analysis using vendor-independent and vendor-specific software in adult and pediatric patients' , JRSM Cardiovascular Disease, vol. 6 , pp. 1-11 , doi:

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Introduction: Two-dimensional strain analysis is a powerful analysis modality, however, clinical utilization has been limited by variability between different analysis systems and operators. We compared strain in adults and children using vendor-specific and vendor-independent software to evaluate variability.Methods: One hundred and ten subjects (50/110 pediatric, 80/110 normal left ventricular function) had echocardiograms with a General Electric ultrasound scanner between September 2010 and January 2012. Left ventricular longitudinal strain was derived with EchoPAC (General Electric, v10.8.1), a vendor-specific software, and Velocity Vector Imaging (Siemens, v3.5), which is vendor-independent. Three independent readers analyzed all the echocardiograms yielding 330 datasets.Results: Mean left ventricular global longitudinal Lagrangian strain was -18.1 ± SD 4.4% for EchoPAC and -15.3 ± SD 4.1% for Velocity Vector Imaging. Velocity Vector Imaging yielded lower absolute global longitudinal Lagrangian strain by mean 2.9 (±SD 2.7, p Conclusion: Velocity Vector Imaging produces lower left ventricular longitudinal strain values versus EchoPAC for the same echo images. Both systems have similar inter-observer variability, Velocity Vector Imaging slightly higher intra-observer variability. A statistically significant change in global longitudinal Lagrangian strain occurs with changes >3-5 strain points on repeat measurements. Strain values between the systems are not interchangeable.

Item Type: Article
Authors/Creators:Anwar, S and Negishi, K and Borowszki, A and Gladding, P and Popovic, ZB and Erenberg, F and Thomas, JD
Keywords: digital imaging and communications in medicine, two-dimensional strain echocardiography, cardiac deformation, left ventricular function, vendor-independent software
Journal or Publication Title: JRSM Cardiovascular Disease
Publisher: Sage Publications Ltd.
ISSN: 2048-0040
DOI / ID Number:
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Copyright 2017 The Authors. Licensed under Creative Commons Attribution-NonCommercial 4.0 International (CC BY-NC 4.0)

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