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Abstract

Background: Tiredness is used in some characterizations of majordepressive disorder (MDD). Transcranial magnetic stimulation (TMS) lowers allsymptoms of MDD. Objective: To explore whether, 1) a visual analogue scale (VAS)for tiredness is a valid and reliable measure of a feature of MDD, and 2) TMStreatment reduces subjective tiredness occurring in MDD. Method: A naturalisticstudy of treatment with 10 Hz TMS. Completed pre- and post-treatment: HAMD-6,a visual analogue scale (VAS-6), the Clinical Global Impression – Severity (CGI-S)and a ‘VAS-tiredness’. Two groups received TMS. Acute course: N=52 participantssuffering acute MDD, received 20 treatment courses (total courses 86). Relapseprevention (RP) course: N=26 participants suffering chronic relapsing MDD receivedscheduled episodic courses over 3 days; (total courses 266). VAS-tiredness scoreswere compared with the standardized tool results. Results: There were significantmedium to large correlations between pre- and post-treatment VAS-tiredness and thestandard depression measures (HAMD-6 .406 to .447, VAS-6 .446 to .525, CGI-S.348 to .407; all pF(1,350)=147.3,pConclusion: -tiredness is a valid measure of afeature of MDD. VAS-tiredness provides potentially useful information and complementsstandard mood tools. TMS treatment can reduce tiredness in MDD.

Item Type:	Article
Authors/Creators:	Pridmore, S and Erger, S and Rybak, M and May, T
Keywords:	VAS-tiredness, MDD, TMS treatment
Journal or Publication Title:	American Journal of Medical Research
Publisher:	Addleton Academic Publishers
ISSN:	2334-4814
DOI / ID Number:	10.22381/AJMR6220191
Copyright Information:	Copyright 2019 Addleton Academic Publishers
Related URLs:	UTAS Profile: Pridmore, S
Item Statistics:	View statistics for this item

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