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Effect of phacoemulsification cataract surgery on intraocular pressure in early glaucoma: a prospective multi-site study

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Abstract
Importance: Cataract and primary open-angle glaucoma (POAG) commonly co-exist, and cataract surgery is thought to reduce intraocular pressure (IOP), the major modifiable risk factor of POAG.Background: Previous studies exploring the effect of cataract surgery on IOP are limited by retrospective design, lack of a control group, medication use and washout and loss to follow up.Design: Prospective, multicentre, matched case-control Australian study.Participants: 171 eyes of 108 POAG patients who underwent cataract surgery, matched to 171 control eyes.Methods: Serial longitudinal IOP measurements were compared before and after cataract surgery, and relative to the controls. A mixed-effect model was used for the longitudinal data.Main Outcome Measures: Change in IOP.Results: The mean follow-up time was 4.8 (1.4) years. Cataract surgery reduced mean IOP by 2.22 mmHg (95% confidence interval: 1.93-2.52 mmHg, P P Conclusions and Relevance: Cataract surgery has a confirmed effect in reducing IOP in a "real world" setting of early glaucoma patients.
Item Type: | Article |
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Authors/Creators: | Qassim, A and Walland, MJ and Landers, J and Awadalla, M and Nguyen, T and Loh, J and Schulz, AM and Ridge, B and Galanopoulos, A and Agar, A and Hewitt, AW and Graham, SL and Healey, PR and Casson, RJ and Craig, JE |
Keywords: | biometry, cataract, cataract surgery, open-angle glaucoma, phacoemulsification |
Journal or Publication Title: | Clinical and Experimental Ophthalmology |
Publisher: | Blackwell Publishing Asia |
ISSN: | 1442-6404 |
DOI / ID Number: | 10.1111/ceo.13724 |
Copyright Information: | Copyright 2020 Royal Australian and New Zealand College of Ophthalmologists |
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