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Correlates of indicators of potential extra-medical opioiduse in people prescribed opioids for chronic non-cancer pain

Santo Jr, T, Larance, B, Bruno, R ORCID: 0000-0001-6673-833X, Gisev, N, Nielsen, S, Degenhardt, L and Campbell, G 2020 , 'Correlates of indicators of potential extra-medical opioiduse in people prescribed opioids for chronic non-cancer pain' , Drug and Alcohol Review, vol. 39 , 128–134 , doi: 10.1111/dar.13021.

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Abstract

Introduction and Aims: The opioid-related behaviours in treatment (ORBIT) scale are a measure of recent indicators ofpotential extra-medical opioid use. Indicators of potential extra-medical opioid use are divergent practices among peopleprescribed opioids that may place them at risk of harm. This study aimed to examine the correlates of indicators of potentialextra-medical opioid use in people prescribed opioids for chronic non-cancer pain (CNCP). Design and Methods: The Painand Opioids IN Treatment (POINT) study is a prospective cohort study of people prescribed opioids for CNCP in Australia.People prescribed opioids solely for opioid dependence were excluded. This cross-sectional study utilised logistic regression todetermine the characteristics associated with reporting any indicators of potential extra-medical opioid use. Results: Of the1505 participants, 38% reported at least one indicator of potential extra-medical opioid use, most commonly asking for anincrease in prescribed opioid dose (21%) and early prescription renewal (12%). Indicators of potential extra-medical opioiduse were associated with younger age (adjusted odds ratio [AOR] = 0.98; 95% confidence interval [CI] = 0.92, 0.99), malesex (AOR = 1.53; 95% CI = 1.15, 2.04), lifetime pharmaceutical opioid use disorder (AOR = 1.87; 95% CI = 1.31,2.66) and lifetime illicit drug use disorder (AOR = 1.72; 95% CI = 1.18, 2.52). Discussion and Conclusions: Overone-third of the POINT cohort reported one or more indicators of potential extra-medical opioid use. Lifetime substance usedisorders were associated these divergent practices, highlighting the importance of clinical monitoring and patient education forthis patient group. Longitudinal studies are needed to investigate whether indicators of potential extra-medical opioid usepredict opioid use disorders in this population.

Item Type: Article
Authors/Creators:Santo Jr, T and Larance, B and Bruno, R and Gisev, N and Nielsen, S and Degenhardt, L and Campbell, G
Keywords: chronic pain, opioid analgesics, addiction, medication adherence, pain management
Journal or Publication Title: Drug and Alcohol Review
Publisher: Carfax Publishing
ISSN: 0959-5236
DOI / ID Number: 10.1111/dar.13021
Copyright Information:

Copyright 2019 Australasian Professional Society on Alcohol and other Drugs

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