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Health-related quality of life, functioning and social experiences in people with psychotic disorders

Nevarez-Flores, AG, Morgan, VA, Harvey, C, Breslin, M ORCID: 0000-0002-8135-3136, Carr, VJ, Sanderson, K ORCID: 0000-0002-3132-2745, Waterreus, A and Neil, AL ORCID: 0000-0002-1344-6672 2020 , 'Health-related quality of life, functioning and social experiences in people with psychotic disorders' , Applied Research in Quality of Life , pp. 1-17 , doi:

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Toinformdevelopmentofamodelforhealth-relatedqualityoflife(HRQoL)inpeoplewith psychotic disorders, we aimed to assess correlations between utilities and dimension scores for the Assessment of Quality of Life (AQoL)-4D with functioning and social experiences; ascertainifpatienthousingandclinicalstatusaffectedcorrelations;anddetermineaspectsof functioningthatjointlypredictHRQoL.Weanalyzeddatafor1642peoplewithanICD-10 psychotic disorder from the 2010 Australian National Survey of Psychosis. Global functioning was measured with the Personal and Social Performance scale, independent functioningwiththeMultidimensionalScaleofIndependentFunctioningandsocialfunctioning through level of social dysfunction. Social experiences comprised perceived loneliness and experienced stigma. We assessed Spearman’s rank correlation coefficients and undertook linear regression analyses. Moderate associations were found between AQoL-4D utilities and all variables, except experienced stigma. Perceived loneliness had the strongest association. The AQoL-4D social relationships dimension was most strongly associated with social variables; its independent livingdimensionwith global and independent functioning. Correlationsbetweenutilitiesandallvariables,exceptforsocialdysfunction,weremodified by housing. Course of disorder impacted correlations with utilities and independent functioning.GlobalfunctioningandsocialdysfunctionwerefoundtojointlypredictHRQoL.In conclusion, as the AQoL-4D can differentiate between functioning and social experiences individually and when categorized by housing and clinical status in people with psychosis, predictive models of HRQoL in this population are feasible, and only need include select aspects of functioning and social experiences, particularly perception of loneliness.

Item Type: Article
Authors/Creators:Nevarez-Flores, AG and Morgan, VA and Harvey, C and Breslin, M and Carr, VJ and Sanderson, K and Waterreus, A and Neil, AL
Keywords: health related quality of life, AQoL-4D, functioning, social experiences, schizophrenia, psychotic disorders, quality of life, lonliness, multi-attribute utility instrument
Journal or Publication Title: Applied Research in Quality of Life
Publisher: Springer Netherlands
ISSN: 1871-2584
DOI / ID Number:
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Copyright 2020 The International Society for Quality-of-Life Studies (ISQOLS) and Springer Nature B.V.

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