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A happiness magnet? Reviewing the evidence for repetitive transcranial magnetic stimulation in major depressive disorder

Pridmore, W and Pridmore, S ORCID: 0000-0002-9170-1798 2020 , 'A happiness magnet? Reviewing the evidence for repetitive transcranial magnetic stimulation in major depressive disorder' , Australasian Psychiatry , pp. 1-7 , doi: 10.1177/1039856220956474.

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Abstract

Objectives:First, to conduct a historical review of the evidence for repetitive transcranial magnetic stimulation (rTMS) for major depressive disorder and determine a clinical algorithm. Second, to identify opportunities for research.Methods:Literature searches were conducted of the MEDLINE database, UpToDate and the Australian National University Library SuperSearch from 1 January 2000 to 30 September 2019. The search terms used were ‘transcranial magnetic stimulation’, ‘major depressive disorder’ and ‘depression’.Results:There were 24 meta-analyses identified, demonstrating a clear clinical effect. Left high-frequency rTMS had the most evidence. Ideal clinical parameters and study design were explored.Conclusion:Use of rTMS for some patients with depression is justified. Open research questions include the comparative efficacy of right low-frequency and bilateral stimulation, the role of rTMS in medication-naïve patients, and maintenance of effect.

Item Type: Article
Authors/Creators:Pridmore, W and Pridmore, S
Keywords: transcranial magnetic stimulation, brain stimulation, major depressive disorder, mood disorder, meta-analysis
Journal or Publication Title: Australasian Psychiatry
Publisher: Sage Publications Ltd.
ISSN: 1039-8562
DOI / ID Number: 10.1177/1039856220956474
Copyright Information:

Copyright 2020 The Royal Australian and New Zealand College of Psychiatrists

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