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Acute kidney injury, stroke and death after cardiopulmonary bypass surgery: the role of perfusion flow and pressure

Turner, L, Hardikar, A, Jose, MD ORCID: 0000-0002-9589-0071, Bhattarai, K, Fenton, C, Sharma, R, Kirkland, G, Jeffs, L, Breslin, M ORCID: 0000-0002-8135-3136, Silva Ragaini, B and Newland, RF 2020 , 'Acute kidney injury, stroke and death after cardiopulmonary bypass surgery: the role of perfusion flow and pressure' , Perfusion (United Kingdom) , pp. 1-9 , doi: 10.1177/0267659120924919.

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Abstract

Introduction: Acute kidney injury after cardiopulmonary bypass surgery is associated with morbidity and mortality. This study aims to evaluate the role of low perfusion flow and pressure in the development of cardiopulmonary bypass-associated acute kidney injury, stroke and death, using multicentre registry data. Methods: We identified patients from the Australian and New Zealand Collaborative Perfusion Registry who underwent coronary artery bypass grafting and/or valvular surgery between 2008 and 2018. Primary predictor variables were the length of time the perfusion flow was 2 and the length of time perfusion pressure was Results: A total of 16,356 patients were included. The mean age was 66 years and 75% were male. Acute kidney injury was observed in 1,844 patients (11%), stroke in 204 (1.3%) and in-hospital death in 286 (1.8%). Neither the duration of the time spent for perfusion flow (2) nor the duration of the time spent for perfusion pressure ( Conclusions: Neither low perfusion pressure nor low perfusion flow during cardiopulmonary bypass were predictive of postoperative acute kidney injury, stroke or death.

Item Type: Article
Authors/Creators:Turner, L and Hardikar, A and Jose, MD and Bhattarai, K and Fenton, C and Sharma, R and Kirkland, G and Jeffs, L and Breslin, M and Silva Ragaini, B and Newland, RF
Keywords: acute kidney injury, cardiopulmonary bypass, perfusion flow, perfusion pressure, stroke
Journal or Publication Title: Perfusion (United Kingdom)
Publisher: Arnold
ISSN: 0267-6591
DOI / ID Number: 10.1177/0267659120924919
Copyright Information:

Copyright 2020 The Authors

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