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Successful bridging therapy in a 103-year-old woman with acute terminal internal carotid artery occlusion


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Nguyen, TQ, Phan, HT ORCID: 0000-0003-0506-2924, Dang, TQ, Tran, VT and Nguyen, TH 2020 , 'Successful bridging therapy in a 103-year-old woman with acute terminal internal carotid artery occlusion' , Case Reports in Neurology, vol. 12, Su , pp. 9-14 , doi: 10.1159/000507693.

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The efficacy of intravenous thrombolysis and endovascular therapy and their favorable treatment outcomes have been established in clinical trials irrespective of age. Current guidelinesdo not recommend an age limit in selecting eligible patients for reperfusion treatment as longas other criteria are satisfied. A 103-year-old woman was admitted at our hospital within 1 hof stroke onset secondary to a left internal carotid artery terminus occlusion. On admission,her National Institutes of Health Stroke Scale (NIHSS) score was 30, with a small left thalamicdiffusion restriction lesion on MRI. Her medical history included paroxysmal atrial fibrillation,prior myocardial infarction, hypertension, chronic kidney disease, and diabetes mellitus. Herpre-stroke modified Rankin Scale score was 0, and she was fully independent before stroke.Once intravenous thrombolysis was started, the patient successfully underwent mechanicalthrombectomy, and thrombolysis in cerebral infarction-3 recanalization was achieved 225 minafter symptom onset. She showed dramatic recovery (NIHSS score of 5 after 48 h) and was discharged on day 7 with a modified Rankin Score of 1. To our knowledge, our patient is thesecond oldest documented patient who successfully underwent bridging therapy for stroke.

Item Type: Article
Authors/Creators:Nguyen, TQ and Phan, HT and Dang, TQ and Tran, VT and Nguyen, TH
Keywords: bridging therapy, stroke, very old patient, Reperfusion treatment, thrombectomy, oldest
Journal or Publication Title: Case Reports in Neurology
Publisher: S. Karger AG
ISSN: 1662-680X
DOI / ID Number: 10.1159/000507693
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© 2020 The Author(s) This article is licensed under the Creative Commons Attribution-NonCommercial 4.0 International License (CC BY-NC)

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