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The impact of 'cluster maintenance TMS' on irritability occurring in major depressive disorder

Pridmore, S ORCID: 0000-0002-9170-1798, Turnier-Shea, Y, Erger, S and May, T 2021 , 'The impact of 'cluster maintenance TMS' on irritability occurring in major depressive disorder' , Australasian Psychiatry, vol. 29, no. 2 , pp. 222-225 , doi: 10.1177/1039856220943033.

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Objective: To determine the impact of clustered maintenance transcranial magnetic stimulation (TMS) on irritability occurring in treatment-resistant major depressive disorder (MDD).Method: A naturalistic study of 106 courses that includes pre- and posttreatment assessments of subjective and objective depression and a subjective measure of irritability developed for this study.Results: Forty-six participants (35 females), mean age 43.2 years (14.3), completed 106 courses. There was a significant reduction in irritability and depression scores (p Conclusion: TMS has the capacity to reduce the irritability co-occurring with treatment-resistant MDD, known to be responsive to TMS. This increases the possibility of using TMS in the treatment of irritability co-occurring with other disorders or standing alone (should irritability be categorized as a stand-alone disorder).

Item Type: Article
Authors/Creators:Pridmore, S and Turnier-Shea, Y and Erger, S and May, T
Keywords: irritability, major depressive disorder, transcranial magnetic stimulation
Journal or Publication Title: Australasian Psychiatry
Publisher: Sage
ISSN: 1039-8562
DOI / ID Number: 10.1177/1039856220943033
Copyright Information:

Copyright 2020 The Royal Australian and New Zealand College of Psychiatrists

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