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Traditional uses, phytochemistry, and pharmacological activities of Cochlospermum tinctorium A. Rich (Cochlospermaceae): a review

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Ahmad, MH, Jatau Abubakar, I, Khalid, GM and Alshargi, OY 2021 , 'Traditional uses, phytochemistry, and pharmacological activities of Cochlospermum tinctorium A. Rich (Cochlospermaceae): a review' , Future Journal of Pharmaceutical Sciences, vol. 7, no. 20 , doi: 10.1186/s43094-020-00168-1.

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Abstract

BackgroundThe plant Cochlospermum tinctorium A. Rich is a sub-shrub that belongs to the family Cochlospermaceae. The plant has been used in traditional medicine for the treatment of malaria, rickets, stomachache, diarrhea, gastric ulcer, parasitic infestations, liver diseases, fever, pain, inflammation, infectious diseases, epilepsy, snake bite, burns, orchitis, labour, menstrual problems, and many other diseases. This review summarizes the traditional uses, phytochemistry, and pharmacological activities of Cochlospermum tinctorium.Main text: To date, few bioactive molecules have been identified and isolated from the plant such as 7,3-dimethyldihydroquercelin, 5,4-dimethylquercelin, cochloxanthine, dihydrocochloxanthine, arjunolic acid, 3-O-E-pcoumaroylalphitolic acid, alphitolic acid, 1-hydroxytetradecan-3-one, 3-bisabolen, 2-tridecanone, 3-hexadecanone, 1-dodecanol, l-tetradecanol, 2-pentdecanone, 3-octadecanone, 1-hydroxy-3-hexadecanone, 1-nonadecanol, l-O-acetyl3-hexadecanone, and l-hydroxy-3-oetadecanone. The literature related some of the reported ethnomedicinal usesof the plant to these compounds found in the different parts of the plant.Conclusion: The comprehensive information documented in this review about the importance of the C. tinctoriummay provide an opportunity for research advancement in drug discovery and a better understanding of themedicinal benefits of the plant.

Item Type: Article
Authors/Creators:Ahmad, MH and Jatau Abubakar, I and Khalid, GM and Alshargi, OY
Keywords: active compounds, Cochlospermum tinctorium, medicinal plant, novel compounds, pharmacological activity, phytochemistry, traditional uses
Journal or Publication Title: Future Journal of Pharmaceutical Sciences
Publisher: SpringerOpen
ISSN: 2314-7253
DOI / ID Number: 10.1186/s43094-020-00168-1
Copyright Information:

Copyright The Author(s). 2021 Open Access This article is licensed under a Creative Commons Attribution 4.0 International License,which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you giveappropriate credit to the original author(s) and the source, provide a link to the Creative Commons licence, and indicate ifchanges were made. The images or other third party material in this article are included in the article's Creative Commonslicence, unless indicated otherwise in a credit line to the material. If material is not included in the article's Creative Commonslicence and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtainpermission directly from the copyright holder. To view a copy of this licence, visit http://creativecommons.org/licenses/by/4.0/.

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