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The Chinese mitten crab genome provides insights into adaptive plasticity and developmental regulation

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Cui, Z, Liu, Y, Yuan, J, Zhang, Y, Ventura, T, Ma, KY, Sun, S, Song, C, Zhan, D, Yang, Y, Liu, H, Fan, G, Cai, Q, Du, J, Qin, J, Shi, C, Hao, S, Fitzgibbon, QP ORCID: 0000-0002-1104-3052, Smith, GG ORCID: 0000-0002-8677-1230, Xiang, J, Chan, T-Y, Hui, M, Bao, C, Li, F and Chu, KH 2021 , 'The Chinese mitten crab genome provides insights into adaptive plasticity and developmental regulation' , Nature Communications, vol. 12, no. 1 , pp. 1-13 , doi: 10.1038/s41467-021-22604-3.

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Abstract

The infraorder Brachyura (true or short-tailed crabs) represents a successful group of marine invertebrates yet with limited genomic resources. Here we report a chromosome-anchored reference genome and transcriptomes of the Chinese mitten crab Eriocheir sinensis, a catadromous crab and invasive species with wide environmental tolerance, strong osmoregulatory capacity and high fertility. We show the expansion of specific gene families in the crab, including F-ATPase, which enhances our knowledge on the adaptive plasticity of this successful invasive species. Our analysis of spatio-temporal transcriptomes and the genome of E. sinensis and other decapods shows that brachyurization development is associated with down-regulation of Hox genes at the megalopa stage when tail shortening occurs. A better understanding of the molecular mechanism regulating sexual development is achieved by integrated analysis of multiple omics. These genomic resources significantly expand the gene repertoire of Brachyura, and provide insights into the biology of this group, and Crustacea in general.

Item Type: Article
Authors/Creators:Cui, Z and Liu, Y and Yuan, J and Zhang, Y and Ventura, T and Ma, KY and Sun, S and Song, C and Zhan, D and Yang, Y and Liu, H and Fan, G and Cai, Q and Du, J and Qin, J and Shi, C and Hao, S and Fitzgibbon, QP and Smith, GG and Xiang, J and Chan, T-Y and Hui, M and Bao, C and Li, F and Chu, KH
Keywords: Chinese mitten crab, genome, transcriptome
Journal or Publication Title: Nature Communications
Publisher: Nature Publishing Group
ISSN: 2041-1723
DOI / ID Number: 10.1038/s41467-021-22604-3
Copyright Information:

© 2021. The Authors. This article is licensed under a Creative Commons Attribution 4.0 International (CC BY 4.0) License, (https://creativecommons.org/licenses/by/4.0/), which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made.

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