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Bioactive Compound Synthetic Capacity and Ecological Significance of Marine Bacterial Genus Pseudoalteromonas

Bowman, JP 2007 , 'Bioactive Compound Synthetic Capacity and Ecological Significance of Marine Bacterial Genus Pseudoalteromonas' , Marine Drugs, vol. 5 , pp. 220-241 , doi:

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The genus Pseudoalteromonas is a marine group of bacteria belonging to the
class Gammaproteobacteria that has come to attention in the natural product and
microbial ecology science fields in the last decade. Pigmented species of the genus have
been shown to produce an array of low and high molecular weight compounds with
antimicrobial, anti-fouling, algicidal and various pharmaceutically-relevant activities.
Compounds formed include toxic proteins, polyanionic exopolymers, substituted
phenolic and pyrolle-containing alkaloids, cyclic peptides and a range of brominesubstituted
compounds. Ecologically, Pseudoalteromonas appears significant and to date
has been shown to influence biofilm formation in various marine econiches; involved in
predator-like interactions within the microbial loop; influence settlement, germination
and metamorphosis of various invertebrate and algal species; and may also be adopted by
marine flora and fauna as defensive agents. Studies have been so far limited to a
relatively small subset of strains compared to the known diversity of the genus
suggesting that many more discoveries of novel natural products as well as ecological
connections these may have in the marine ecosystem remain to be made.

Item Type: Article
Authors/Creators:Bowman, JP
Keywords: Pseudoalteromonas, antibiotics, biofilms, anti-fouling, marine bacteria.
Journal or Publication Title: Marine Drugs
Publisher: Molecular Diversity Preservation International
ISSN: 1660-3397
DOI / ID Number:
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