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Response inhibition in humans: a whistle stop review

Nikitenko, T ORCID: 0000-0002-9705-1386, Chowdhury, N, Puri, R ORCID: 0000-0002-0231-1369 and He, JL 2019 , 'Response inhibition in humans: a whistle stop review' , Journal of Neurophysiology, vol. 123 , pp. 861-864 , doi: 10.1152/jn.00572.2019.

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Abstract

This Neuro Forum presents insights from recent literature on the neurophysiology and pathoneurophysiology of reactive (speed of action stopping) and proactive (slowing of action in anticipation of stopping) response inhibition. We discuss recent studies using novel brain stimulation and spectroscopy techniques that reveal the role of cortico-subcortical networks and the neurotransmitter γ-aminobutyric acid (GABA) and how these mechanisms are influenced by healthy aging. Furthermore, we also briefly discuss computational modeling approaches, which assist in establishing meaningful differences in response inhibition.

Item Type: Article
Authors/Creators:Nikitenko, T and Chowdhury, N and Puri, R and He, JL
Keywords: transcranial magnetic stimulation, motor control, ageing
Journal or Publication Title: Journal of Neurophysiology
Publisher: Amer Physiological Soc
ISSN: 0022-3077
DOI / ID Number: 10.1152/jn.00572.2019
Copyright Information:

Copyright © 2020 the American Physiological Society

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