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Early relapse treatment (ERT) or “maintenance” transcranial magnetic stimulation (TMS)?


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Pridmore, S ORCID: 0000-0002-9170-1798, Erger, S, Rybak, M, Kelly, E and Lawson, F 2017 , 'Early relapse treatment (ERT) or “maintenance” transcranial magnetic stimulation (TMS)?' , American Journal of Medical Research, vol. 4, no. 1 , pp. 111-117 .

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Background: Major depressive disorder (MDD) commonly takes a relapsing form. Transcranial magnetic stimulation (TMS) has be suggested as a means of maintaining remission. Brief courses of TMS at about monthly intervals appear to provide health benefits. Objective: To examine whether such brief courses of TMS are better conceptualized as maintaining remission, or as the provision of early relapse treatment. Method: 25 series of treatment (18 different patients) were considered. Pre- and post-treatment 6-item Hamilton Depression Rating Scale (HAMD6) and 7 visual analogue scales (VASs) were collected, along with pretreatment Clinical Global Impression-Severity (CGI-S) and post-treatment CGIImprovement (I). Results: Pre-treatment HAMD6 and CGI-S indicated that many patients were symptomatic and in early relapse. Post-treatment HAMD6 indicated that many patients had achieved remission, and this was supported by the CGI-I. The VAS scores also improved. Conclusions: Short courses of TMS at about monthly intervals have beneficial results and are better conceptualized as early relapse treatment (ERT).

Item Type: Article
Authors/Creators:Pridmore, S and Erger, S and Rybak, M and Kelly, E and Lawson, F
Keywords: major depressive disorder, transcranial magnetic stimulation, early relapse treatment
Journal or Publication Title: American Journal of Medical Research
Publisher: Addleton Academic Publishers
ISSN: 2334-4814
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© 2009 Addleton Academic Publishers. All Rights Reserved.

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