Open Access Repository

Stability of cabergoline in fox baits in laboratory and field conditions


Downloads per month over past year

McLean, SR, Brandon, S and Kirkwood, R 2007 , 'Stability of cabergoline in fox baits in laboratory and field conditions' , Wildlife Research, vol. 34, no. 3 , pp. 239-246 , doi: 10.1071/WR06094.

[img] PDF
3956.pdf | Request a copy
Full text restricted
Available under University of Tasmania Standard License.


Cabergoline is a potent inhibitor of prolactin release and a potential fertility control agent for foxes. To understand how cabergoline could behave in baits deployed for fox control, we conducted laboratory and field trials to investigate the stability of cabergoline when (1) in solution, (2) injected into a bait (deep-fried liver and Foxoff®) and (3) exposed to a range of environmental conditions, including burial. Cabergoline, dissolved in a 1% acetic acid solution, and its carboxylic acid hydrolysis product can be assayed using high-performance liquid chromatography. When stored at 4°C and at room temperature, cabergoline in solution was stable for up to 36 days. When stored under cool (≤15°C), dry conditions, cabergoline (800 µg) in commercial Foxoff® and deep-fried ox-liver baits was stable for 28 and 7 days, respectively; stability was reduced by increases in temperature (tested up to 40°C) and humidity. Recovery of cabergoline from buried baits exposed to a range of field conditions decreased rapidly in the first week, but after 56 days remained detectable at levels of 6–22% of the injected amounts. This study has important implications for baiting campaigns that use cabergoline for fox control.

Item Type: Article
Authors/Creators:McLean, SR and Brandon, S and Kirkwood, R
Journal or Publication Title: Wildlife Research
Publisher: CSIRO Publishing
ISSN: 1035-3712
DOI / ID Number: 10.1071/WR06094
Additional Information:

Copyright © 2007 CSIRO.

Item Statistics: View statistics for this item

Actions (login required)

Item Control Page Item Control Page